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1

Identification of anti-HIV active dicaffeoylquinic- and tricaffeoylquinic acids in Helichrysum populifolium by NMR-based metabolomic guided fractionation

Heyman, Heino Martin, Senejoux, François, Seibert, Isabell, Klimkait, Thomas, Maharaj, Vinesh Jaichand, Meyer, Jacobus Johannes Marion

Journal:

Year:

2015

Language:

english

File:

PDF, 1.05 MB

english, 2015

2

Antigen-specific adaptive immune responses in fingolimod-treated multiple sclerosis patients

Matthias Mehling, Patricia Hilbert, Stefanie Fritz, Bojana Durovic, Dominik Eichin, Olivier Gasser, Jens Kuhle, Thomas Klimkait, Raija L.P. Lindberg, Ludwig Kappos, Christoph Hess

Journal:

Annals of Neurology

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

3

Ethnopharmacology in overdrive: The remarkable anti-HIV activity of Artemisia annua

Andrea Lubbe, Isabell Seibert, Thomas Klimkait, Frank van der Kooy

Journal:

Journal of Ethnopharmacology

Year:

2012

Language:

english

File:

PDF, 242 KB

english, 2012

4

Same day ART initiation versus clinic-based pre-ART assessment and counselling for individuals newly tested HIV-positive during community-based HIV testing in rural Lesotho – a randomized controlled trial (CASCADE trial)

Labhardt, Niklaus Daniel, Ringera, Isaac, Lejone, Thabo Ishmael, Masethothi, Phofu, Thaanyane, T’sepang, Kamele, Mashaete, Gupta, Ravi Shankar, Thin, Kyaw, Cerutti, Bernard, Klimkait, Thomas, Fritz, C

Journal:

BMC Public Health

Year:

2016

Language:

english

File:

PDF, 737 KB

english, 2016

5

Effect of Offering Same-Day ART vs Usual Health Facility Referral During Home-Based HIV Testing on Linkage to Care and Viral Suppression Among Adults With HIV in Lesotho

Labhardt, Niklaus D., Ringera, Isaac, Lejone, Thabo I., Klimkait, Thomas, Muhairwe, Josephine, Amstutz, Alain, Glass, Tracy R.

Journal:

JAMA The Journal of the American Medical Association

Year:

2018

Language:

english

File:

PDF, 368 KB

english, 2018

6

SESOTHO trial (“Switch Either near Suppression Or THOusand”) – switch to second-line versus WHO-guided standard of care for unsuppressed patients on first-line ART with viremia below 1000 copies/mL: protocol of a multicenter, parallel-group, open-label, randomized clinical trial in Lesotho, Southern Africa

Amstutz, Alain, Nsakala, Bienvenu Lengo, Vanobberghen, Fiona, Muhairwe, Josephine, Glass, Tracy Renée, Achieng, Beatrice, Sepeka, Mamorena, Tlali, Katleho, Sao, Lebohang, Thin, Kyaw, Klimkait, Thomas,

Journal:

BMC Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 680 KB

english, 2018

7

Phylogenetic Cluster Analysis Identifies Virological and Behavioral Drivers of HIV Transmission in MSM

Bachmann, Nadine, Kusejko, Katharina, Nguyen, Huyen, Chaudron, Sandra E, Kadelka, Claus, Turk, Teja, BÃ¶ni, JÃ¼rg, Perreau, Matthieu, Klimkait, Thomas, Yerly, Sabine, Battegay, Manuel, Rauch, Andri, R

Journal:

Clinical Infectious Diseases

Year:

2020

File:

PDF, 1.28 MB

2020

8

Rational optimization of a HIV-1 Tat inhibitor: Rapid progress on combinatorial lead structures

Thomas Klimkait, Eduard R. Felder, Geneviève Albrecht, François Hamy

Journal:

Biotechnology and Bioengineering

Year:

1999

Language:

english

File:

PDF, 1.29 MB

english, 1999

9

Synthesis of Potent and Orally Active HIV-Protease Inhibitors

Hans-Georg Capraro, Guido Bold, Alexander Fässler, Robert Cozens, Thomas Klimkait, Janis Lazdins, Jürgen Mestan, Bernard Poncioni, Johannes L. Rösel, David Stover, Marc Lang

Journal:

Archiv der Pharmazie

Year:

1996

Language:

english

File:

PDF, 681 KB

english, 1996

10

Design, synthesis and evaluation of potential inhibitors of HIV gp120–CD4 interactions

Cyrille Boussard, Thomas Klimkait, Naheed Mahmood, Martin Pritchard, Ian H. Gilbert

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 295 KB

english, 2004

11

Blocking HIV replication by targeting Tat protein

François Hamy, Nathalie Gelus, Marco Zeller, Janis L Lazdins, Christian Bailly, Thomas Klimkait

Journal:

Chemistry & Biology

Year:

2000

Language:

english

File:

PDF, 503 KB

english, 2000

12

High specificity of line-immunoassay based algorithms for recent HIV-1 infection independent of viral subtype and stage of disease

Jörg Schüpbach, Leslie R Bisset, Stephan Regenass, Philippe Bürgisser, Meri Gorgievski, Ingrid Steffen, Corinne Andreutti, Gladys Martinetti, Cyril Shah, Sabine Yerly, Thomas Klimkait, Martin Gebhardt

Journal:

BMC Infectious Diseases

Year:

2011

Language:

english

File:

PDF, 272 KB

english, 2011

13

Design, synthesis and evaluation of peptide libraries as potential anti-HIV compounds, via inhibition of gp120/cell membrane interactions, using the gp120/cd4/fab17 crystal structure

Cyrille Boussard, Valerie E Doyle, Naheed Mahmood, Thomas Klimkait, Martyn Pritchard, Ian H Gilbert

Journal:

European Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 674 KB

english, 2002

14

Inhibition of HIV-1 Tat-TAR interaction by diphenylfuran derivatives: effects of the terminal basic side chains

Nathalie Gelus, Christian Bailly, François Hamy, Thomas Klimkait, W.David Wilson, David W. Boykin

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 236 KB

english, 1999

15

A syncytia assay for human immunodeficiency virus type I(H IV-I) envelope protein and its use in studying HIV-I mutations

James M. Felser, Thomas Klimkait, Jonathan Silver

Journal:

Year:

1989

Language:

english

File:

PDF, 2.69 MB

english, 1989

16

Mutations within the human immunodeficiency virus type 1 gp160 envelope glycoprotein alter its intracellular transport and processing

Ronald L. Willey, Thomas Klimkait, David M. Frucht, Juan S. Bonifacinot, Malcolm A. Martin

Journal:

Year:

1991

Language:

english

File:

PDF, 1.14 MB

english, 1991

17

Thiated derivatives of 2′,3′-dideoxy-3′-fluorothymidine: Synthesis, in vitro anti-HIV-1 activity and interaction with recombinant drug resistant HIV-1 reverse transcriptase forms

Agnieszka Miazga, François Hamy, Séverine Louvel, Thomas Klimkait, Zofia Pietrusiewicz, Anna Kurzyńska-Kokorniak, Marek Figlerowicz, Patrycja Wińska, Tadeusz Kulikowski

Journal:

Antiviral Research

Year:

2011

Language:

english

File:

PDF, 296 KB

english, 2011

18

Association of Human Immunodeficiency Virus Nef Protein with Actin is Myristoylation Dependent and Influences its Subcellular Localization

Oliver T. Fackler, Norbert Kienzle, Elisabeth Kremmer, Annette Boese, Birgit Schramm, Thomas Klimkait, Claudia Kücherer, Nikolaus Mueller-Lantzsch

Journal:

Year:

1997

Language:

english

File:

PDF, 1.16 MB

english, 1997

19

Bioassay-Guided Investigation of the Tanzanian Plant Pyrenacantha kaurabassana for Potential Anti-HIV-Active Compounds

Omolo, Justin J., Maharaj, Vinesh, Naidoo, Dashnie, Klimkait, Thomas, Malebo, Hamisi M., Mtullu, Samwel, Lyaruu, Herbert V. M., Koning, Charles B. de

Journal:

Journal of Natural Products

Year:

2012

Language:

english

File:

PDF, 332 KB

english, 2012

20

A Picomolar Inhibitor of Resistant Strains of Human Immunodeficiency Virus Protease Identified by a Combinatorial Approach

Markéta Rinnová, Martin Hradilek, Cyril Bařinka, Jan Weber, Milan Souček, Jiřı́ Vondrášek, Thomas Klimkait, Jan Konvalinka

Journal:

Archives of Biochemistry and Biophysics

Year:

2000

Language:

english

File:

PDF, 684 KB

english, 2000

21

E1B functions of type C adenoviruses play a role in the complementation of blocked adenovirus type 12 DNA replication and late gene transcription in hamster cells

Thomas Klimkait, Walter Doerfler

Journal:

Year:

1987

Language:

english

File:

PDF, 1.22 MB

english, 1987

22

In vivo evolution of adenovirus 2-transformed cell virulence associated with altered E1A gene function

James L. Cook, Andrew M. Lewis Jr., Thomas Klimkait, Birgitt Knust, Walter Doerfler, Thomas A. Walker

Journal:

Year:

1988

Language:

english

File:

PDF, 3.80 MB

english, 1988

23

The peptidyl–prolyl isomerase Pin1 regulates phospho-Ser77 retinoic acid receptor α stability

Vincent Brondani, Quirino Schefer, François Hamy, Thomas Klimkait

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 642 KB

english, 2005

24

Natural polymorphisms in the protease gene modulate the replicative capacity of non-B HIV-1 variants in the absence of drug pressure

Africa Holguín, Carlos Suñe, François Hamy, Vincent Soriano, Thomas Klimkait

Journal:

Journal of Clinical Virology

Year:

2006

Language:

english

File:

PDF, 166 KB

english, 2006

25

Contrary to HIV, hepatitis C virus is not associated with erythrocytes in vivo

Salima Sadallah, Markus Heim, Christoph Hess, Thomas Klimkait, Manuel Battegay, Jürg A. Schifferli

Journal:

Journal of Hepatology

Year:

2005

Language:

english

File:

PDF, 61 KB

english, 2005

26

Enhanced gene silencing by the application of multiple specific small interfering RNAs

Jingmin Ji, Marion Wernli, Thomas Klimkait, Peter Erb

Journal:

Year:

2003

Language:

english

File:

PDF, 419 KB

english, 2003

27

Erratum to: Enhanced gene silencing by the application of multiple specific small interfering RNAs (FEBS 27581): [FEBS Letters 552 (2003) 247–252]

Jingmin Ji, Marion Wernli, Thomas Klimkait, Peter Erb

Journal:

Year:

2003

Language:

english

File:

PDF, 31 KB

english, 2003

28

Promoter of FGF8 Reveals a Unique Regulation by Unliganded RARα

Vincent Brondani, Thomas Klimkait, Jean-Marc Egly, François Hamy

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 659 KB

english, 2002

29

Association of a pool of HIV-1 with erythrocytes in vivo: a cohort study

Christoph Hess, Thomas Klimkait, Luregn Schlapbach, Veronika Del Zenero, Salima Sadallah, Eliska Horakova, Gianmarco Balestra, Verena Werder, Christoph Schaefer, Manuel Battegay, Jürg-Alfred Schifferl

Journal:

Year:

2002

Language:

english

File:

PDF, 361 KB

english, 2002

30

Recombination Between Variants from Genital Tract and Plasma: Evolution of Multidrug-Resistant HIV Type 1

Kemal, Kimdar S., Ramirez, Christina M., Burger, Harold, Foley, Brian, Mayers, Douglas, Klimkait, Thomas, Hamy, François, Anastos, Kathryn, Petrovic, Katarina, Minin, Vladimir N., Suchard, Marc A., We

Journal:

AIDS Research and Human Retroviruses

Year:

2012

Language:

english

File:

PDF, 451 KB

english, 2012

31

New Aza-Dipeptide Analogues as Potent and Orally Absorbed HIV-1 Protease Inhibitors: Candidates for Clinical Development

Bold, Guido, Fässler, Alexander, Capraro, Hans-Georg, Cozens, Robert, Klimkait, Thomas, Lazdins, Janis, Mestan, Jürgen, Poncioni, Bernard, Rösel, Johannes, Stover, David, Tintelnot-Blomley, Marina, Ac

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 240 KB

english, 1998

32

Round-table multidisciplinary counselling of couples with HIV prior to assisted reproduction

Sibil Tschudin, Sabine Steimann, Johannes Bitzer, Irene Hösli, Wolfgang Holzgreve, Luigia Elzi, Thomas Klimkait, Christoph Rudin, Manuel Battegay, Christian De Geyter

Journal:

Reproductive BioMedicine Online

Year:

2008

Language:

english

File:

PDF, 538 KB

english, 2008

33

Diagnostic performance of line-immunoassay based algorithms for incident HIV-1 infection

Jörg Schüpbach, Leslie R Bisset, Martin D Gebhardt, Stephan Regenass, Philippe Bürgisser, Meri Gorgievski, Thomas Klimkait, Corinne Andreutti, Gladys Martinetti, Christoph Niederhauser, Sabine Yerly,

Journal:

BMC Infectious Diseases

Year:

2012

Language:

english

File:

PDF, 252 KB

english, 2012

34

Prospective Study of Polyomavirus Type BK Replication and Nephropathy in Renal-Transplant Recipients

Hirsch, Hans H., Knowles, Wendy, Dickenmann, Michael, Passweg, Jakob, Klimkait, Thomas, Mihatsch, Michael J., Steiger, Jürg

Journal:

Boston Medical and Surgical Journal

Year:

2002

Language:

english

File:

PDF, 126 KB

english, 2002

35

A New Class of HIV-1 Tat Antagonist Acting through Tat−TAR Inhibition

Hamy, François, Brondani, Vincent, Flörsheimer, Andreas, Stark, Wilhelm, Blommers, Marcel J. J., Klimkait, Thomas

Journal:

Year:

1998

Language:

english

File:

PDF, 186 KB

english, 1998

36

The XTrack System: Application and Advantage

Klimkait, Thomas

Journal:

Year:

2012

Language:

english

File:

PDF, 512 KB

english, 2012

37

Lack of effect of desferrioxamine on in-vitro HIV-1 replication

Lazdins, JanisK., Alteri, Enrica, Klimkait, Thomas, Woods-Cook, Kathie, Walker, MajaR., Goutte, Gerard, Poncioni, Bernard

Journal:

Year:

1991

Language:

english

File:

PDF, 355 KB

english, 1991

38

Reactivation of the methylation-inactivated late E2A promoter of adenovirus type 2 by E1A (13 S) functions

Weisshaar, Bernd, Langner, Klaus-Dieter, Jüttermann, Ruth, Müller, Ulrich, Zock, Christiane, Klimkait, Thomas, Doerfler, Walter

Journal:

Journal of Molecular Biology

Year:

1988

Language:

english

File:

PDF, 5.49 MB

english, 1988

39

An Inhibitor of the Tat/TAR RNA Interaction that Effectively Suppresses HIV-1 Replication

Francois Hamy, Eduard R. Felder, Gerhard Heizmann, Jains Lazdins, Fareed Aboul-Ela, Gabriele Varani, Jonathan Karn and Thomas Klimkait

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.69 MB

english, 1997

40

Testing for Polyomavirus Type BK DNA in Plasma to Identify Renal-Allograft Recipients with Viral Nephropathy

Nickeleit, Volker, Klimkait, Thomas, Binet, Isabelle F., Dalquen, Peter, Del Zenero, Veronika, Thiel, Gilbert, Mihatsch, Michael J., Hirsch, Hans H.

Journal:

Boston Medical and Surgical Journal

Year:

2000

Language:

english

File:

PDF, 165 KB

english, 2000

41

Library-Based Discovery and Characterization of Daphnane Diterpenes as Potent and Selective HIV Inhibitors in Daphne gnidium

Vidal, Vincent, Potterat, Olivier, Louvel, Séverine, Hamy, François, Mojarrab, Mahdi, Sanglier, Jean-Jacques, Klimkait, Thomas, Hamburger, Matthias

Journal:

Journal of Natural Products

Year:

2012

Language:

english

File:

PDF, 1.82 MB

english, 2012

42

Higher Risk of Incident Hepatitis C Virus Coinfection Among Men Who Have Sex With Men, in Whom the HIV Genetic Bottleneck at Transmission Was Wide

Kouyos, Roger D., Rauch, Andri, Braun, Dominique L., Yang, Wan-Lin, Böni, Jürg, Yerly, Sabine, Klimkait, Thomas, Aubert, Vincent, Shah, Cyril, Kovari, Helen, Calmy, Alexandra, Cavassini, Matthias, Bat

Journal:

The Journal of Infectious Diseases

Year:

2014

Language:

english

File:

PDF, 225 KB

english, 2014

43

A Diagnostic HIV-1 Tropism System Based on Sequence Relatedness

Edwards, Suzanne, Stucki, Heinz, Bader, Joëlle, Vidal, Vincent, Kaiser, Rolf, Battegay, Manuel, Klimkait, Thomas, Tang, Y.-W.

Journal:

Journal of Clinical Microbiology

Year:

2015

Language:

english

File:

PDF, 3.44 MB

english, 2015

44

In vitro Effect of$\alpha_{1}$-Acid Glycoprotein on the Anti-Human Immunodeficiency Virus (HIV) Activity of the Protease Inhibitor CGP 61755: A Comparative Study with Other Relevant HIV Protease Inhibitors

Janis K. Lazdins, Jürgen Mestan, Gerard Goutte, Maja R. Walker, Guido Bold, Hans Georg Capraro and Thomas Klimkait

Journal:

The Journal of Infectious Diseases

Year:

1997

Language:

english

File:

PDF, 1.33 MB

english, 1997

45

Development of a simple microarray for genotyping HIV-1 drug resistance mutations in the reverse transcriptase gene in rural Tanzania

Masimba, Pax, Gare, Janet, Klimkait, Thomas, Tanner, Marcel, Felger, Ingrid

Journal:

Tropical Medicine & International Health

Year:

2014

Language:

english

File:

PDF, 211 KB

english, 2014

46

The Replicative Restriction of Lymphocytotropic Isolates of HIV-1 in Macrophages Is Overcome by TGF-β

LAZDINS, JANIS K., KLIMKAIT, THOMAS, WOODS-COOK, KATHIE, WALKER, MAJA, ALTERI, ENRICA, COX, DAVID, CERLETTI, NICO, SHIPMAN, ROBERT, BILBE, GRAHAM, McMASTER, GARY

Journal:

AIDS Research and Human Retroviruses

Year:

1992

Language:

english

File:

PDF, 1.95 MB

english, 1992

47

Synthesis of Potential Anti-HIV GP120 Inhibitors Using a Lysine Template

Doyle, Valerie E., Klimkait, Thomas, Mahmood, Naheed, Slater, Martin, Hazen, Richard J., Gilbert, Ian H.

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 245 KB

english, 2002

48

Prevalence of Drug-Resistance Mutations and HIV-1 Subtypes in a HIV-1 Infected COHORT in rural Tanzania

Masimba, Pax Jessey, Kituma, Elimsaada, Klimkait, Thomas, Horvath, Edit, Stoeckle, Marcel, Hatz, Christoph, Mossdorf, Erick, Mwaigomole, Emmanuel, Hamis, Salim, Jullu, Boniface, Abdulla, Salim, Tanner

Journal:

AIDS Research and Human Retroviruses

Year:

2013

Language:

english

File:

PDF, 213 KB

english, 2013

49

Limited clinical benefit of minority K103N and Y181C-variant detection in addition to routine genotypic resistance testing in antiretroviral therapy-naive patients

Metzner, Karin J., Scherrer, Alexandra U., von Wyl, Viktor, Böni, Jürg, Yerly, Sabine, Klimkait, Thomas, Aubert, Vincent, Furrer, Hansjakob, Hirsch, Hans H., Vernazza, Pietro L., Cavassini, Matthias,

Journal:

Year:

2014

Language:

english

File:

PDF, 241 KB

english, 2014

50

Long‐Term Trends of HIV Type 1 Drug Resistance Prevalence among Antiretroviral Treatment–Experienced Patients in Switzerland

von Wyl, Viktor, Yerly, Sabine, Böni, Jürg, Bürgisser, Philippe, Klimkait, Thomas, Battegay, Manuel, Bernasconi, Enos, Cavassini, Matthias, Furrer, Hansjakob, Hirschel, Bernard, Vernazza, Pietro L., F

Journal:

Clinical Infectious Diseases

Year:

2009

Language:

english

File:

PDF, 495 KB

english, 2009

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